Timothy M. Uyeki, MD, MPH, MPP
CME Objective: To review current evidence for prevention, diagnosis, treatment, and practice improvement of influenza.
Funding Source: American College of Physicians.
Acknowledgment: The author thanks Margaret Trexler Hessen, MD, author of the previous version of this In the Clinic.
Disclaimer: The views expressed are those of the author and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
With the assistance of additional physician writers, the editors of Annals of Internal Medicine develop In the Clinic using MKSAP and other resources of the American College of Physicians.
In the Clinic does not necessarily represent official ACP clinical policy. For ACP clinical guidelines, please go to https://www.acponline.org/clinical_information/guidelines/.
Disclosures: Dr. Uyeki, ACP Contributing Author, has disclosed no conflicts of interest. His form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M17-1783.
Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that she has no financial relationships or interests to disclose. Darren B. Taichman, MD, PhD, Executive Deputy Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Deborah Cotton, MD, MPH, Deputy Editor, reports that she has no financial relationships or interest to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Catharine B. Stack, PhD, MS, Deputy Editor for Statistics, reports that she has stock holdings in Pfizer and Johnson & Johnson.
Influenza is an acute viral respiratory disease that affects persons of all ages and is associated with millions of medical visits, hundreds of thousands of hospitalizations, and thousands of deaths during annual winter epidemics of variable severity in the United States. Elderly persons have the highest influenza-associated hospitalization and mortality rates. The primary method of prevention is annual vaccination. Early antiviral treatment has the greatest clinical benefit; otherwise, management includes adherence to recommended infection prevention and control measures as well as supportive care of complications.
Uyeki TM. Influenza. Ann Intern Med. 2017;167:ITC33–ITC48. doi: https://doi.org/10.7326/AITC201709050
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Published: Ann Intern Med. 2017;167(5):ITC33-ITC48.
Infectious Disease, Influenza, Prevention/Screening, Pulmonary/Critical Care, Vaccines/Immunization.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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