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ACP Journal Club |16 January 2018

Guideline: Experts recommend a single dose of oral steroids for pain relief in acute sore throat

Alexander W. Chessman, MD

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Aertgeerts B, Agoritsas T, Siemieniuk RA, et al. Corticosteroids for sore throat: a clinical practice guideline. BMJ. 2017;358:j4090. 28931507

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Emergency Med:

To review evidence and provide recommendations for the use of corticosteroids in patients with acute sore throat.
An international expert panel developed a recommendation for adding corticosteroids to standard care in adults and children ≥ 5 years of age with acute sore throat. The recommendation was based on a systematic review {with searches done to May 2017}*. The review included 10 randomized controlled trials (RCTs) (n = 1426, mean age 26 y, 57% women): 5 evaluated oral dexamethasone, 3 intramuscular dexamethasone, and 1 each evaluated prednisone and betamethasone. 8 RCTs (n = 771) were done in emergency departments, and 2 (n = 655) in primary care practices. The panel comprised an otorhinolaryngologist, pediatricians, general practitioners, general internists, epidemiologists, methodologists, statisticians, and patients. They appraised evidence and developed recommendations using the GRADE approach and considered feedback from journal peer reviewers, practical intervention issues, patient preferences and values, and resource use.
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Chessman AW. Guideline: Experts recommend a single dose of oral steroids for pain relief in acute sore throat. Ann Intern Med. ;168:JC2. doi: 10.7326/ACPJC-2018-168-2-002

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Published: Ann Intern Med. 2018;168(2):JC2.

DOI: 10.7326/ACPJC-2018-168-2-002

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2018 American College of Physicians
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