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Letters |20 November 2018

Omalizumab Rescue Therapy for Refractory Status Asthmaticus

Katrin Milger, MD; Ines Schroeder, MD; Jürgen Behr, MD; Tobias Meis, MD; Werner v. Wulffen, MD, PhD; Nikolaus Kneidinger, MD, PhD

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This article was published at Annals.org on 20 November 2018.
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Background: Despite advances in asthma therapy, asthma mortality has remained stable in recent years (1). One reason is status asthmaticus, which can be unresponsive to initial treatment and may lead to hypercapnic respiratory failure despite maximal therapy.
Objective: To alert clinicians to the possibility of a new rescue option for status asthmaticus.
Case Report: A 41-year-old man developed severe dyspnea while working at an outside construction site. The patient had a history of asthma with pollen allergy. He had not consulted a respiratory physician recently but had been using a short-acting β2-agonist inhaler several times daily for several weeks. The emergency physician who arrived at the site noted severe wheezing and intubated the patient for respiratory failure, and the patient was hospitalized.
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Milger K, Schroeder I, Behr J, Meis T, Wulffen WV, Kneidinger N. Omalizumab Rescue Therapy for Refractory Status Asthmaticus. Ann Intern Med. [Epub ahead of print ]:. doi: 10.7326/L18-0359

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Published: Ann Intern Med. 2018.

DOI: 10.7326/L18-0359

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2018 American College of Physicians
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