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Letters |15 October 2019

Fanconi Syndrome and Tenofovir Alafenamide

Nathan C. Bahr, MD; Sri G. Yarlagadda, MD

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IN RESPONSE:
We appreciate Drs. Álvarez and Llibre's thoughtful discussion of our recent case report and the additional cases that we cited. We particularly appreciate their clarifying their belief that the patient in their previous case report (1) who intentionally overdosed on antiretroviral medications that included TAF had acute tubular necrosis due to decreased intravascular volume and not TAF.
Our patient had been receiving TDF, ritonavir-boosted darunavir, and rosuvastatin for many years before his previous provider initiated a switch from TDF to TAF therapy. One month before this switch, his renal function was normal as it had been...
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Bahr NC, Yarlagadda SG. Fanconi Syndrome and Tenofovir Alafenamide. Ann Intern Med. 2019;171:599–600. doi: https://doi.org/10.7326/L19-0477

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Published: Ann Intern Med. 2019;171(8):599-600.

DOI: 10.7326/L19-0477

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2019 American College of Physicians
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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