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ACP Journal Club |19 November 2019

Review: No high-certainty evidence exists that nutritional supplements or diets affect cardiovascular outcomes

Lawrence J. Cheskin, MD, FACP; Margaret Slavin, PhD, RDN

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Khan SU, Khan MU, Riaz H, et al. Effects of nutritional supplements and dietary interventions on cardiovascular outcomes: an umbrella review and evidence map. Ann Intern Med. 2019;171:190-8. 31284304

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In adults, what is the efficacy of nutritional supplements and dietary interventions for prevention of mortality and cardiovascular (CV) outcomes?
Included English-language articles assessed nutritional supplements (vitamins, minerals, dietary supplements) or dietary interventions in adults. Outcomes were all-cause mortality, CV mortality, myocardial infarction, stroke, and coronary heart disease.
PubMed, CINAHL, and Cochrane Library (all to Mar 2019); ClinicalTrials.gov; journal Web sites; and reference lists were searched for...
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Cheskin LJ, Slavin M. Review: No high-certainty evidence exists that nutritional supplements or diets affect cardiovascular outcomes. Ann Intern Med. 2019;171:JC50. doi: https://doi.org/10.7326/ACPJ201911190-050

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Published: Ann Intern Med. 2019;171(10):JC50.

DOI: 10.7326/ACPJ201911190-050

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2019 American College of Physicians
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