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Letters |3 December 2019

Heart Failure From Gouty Myocarditis: A Case Report

Andrea Frustaci, MD; Matteo Antonio Russo, MD; Luigi Sansone, PhD; Marco Francone, MD, PhD; Romina Verardo, PhD; Claudia Grande, PhD; Maria Alfarano, MD; Cristina Chimenti, MD, PhD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
This article was published at Annals.org on 3 December 2019.
  • Sapienza University and IRCCS L. Spallanzani, Rome, Italy (A.F., C.C.)
    San Raffaele Open University and IRCCS San Raffaele Pisana, Rome, Italy (M.A.R.)
    IRCCS San Raffaele Pisana, Rome, Italy (L.S.)
    Sapienza University, Rome, Italy (M.F., M.A.)
    IRCCS L. Spallanzani, Rome, Italy (R.V., C.G.)

    Financial Support: By grant JTC 2016 IKDT-IGCM from the European Research Area Network on Cardiovascular Diseases under European Project ERA-CVD “Transnational Research Projects on Cardiovascular Diseases” and by Italian Ministry of Health (Ricerca Corrente) funds given to IRCCS L. Spallanzani and IRCCS San Raffaele Pisana.

    Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L19-0486.

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Background: Myocarditis is an important cause of heart failure, and successful treatment depends on identifying the underlying cause and mechanism. Infectious and autoimmune diseases are the most common causes, although myocarditis can also be caused by endocrine disorders, such as pheochromocytoma (1); infiltrative disorders, such as amyloidosis (2); and metabolic disorders. Gout is a metabolic disorder characterized by increased uric acid in the blood and the deposition of amorphous urate crystals that cause a vigorous inflammatory reaction in the joints, kidneys, and soft tissues. Urate crystals have been found in coronary vessels and cardiac valves but,...
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Frustaci A, Russo MA, Sansone L, et al. Heart Failure From Gouty Myocarditis: A Case Report. Ann Intern Med. 2019;:. [Epub ahead of print 3 December 2019]. doi: https://doi.org/10.7326/L19-0486

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Published: Ann Intern Med. 2019.

DOI: 10.7326/L19-0486

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2019 American College of Physicians
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