Stanislas Pol, MD; Bertrand Nalpas, MD, PhD; Pierre Berthelot, MD
This content is PDF only. Please click on the PDF icon to access.
To the editors: The alcohol withdrawal syndrome (AWS) is related to an increase in sympathetic nervous system activity and to a reduction in the threshold of neuronal excitability. Patients undergoing alcohol withdrawal require pharmacologic treatment because of the risk, possibly lethal, of delirium tremens. Pharmacologic treatment (usually based on neuroleptic, sedative, or anxiolytic drugs) is problematic in patients with hepatocellular failure, in whom iatrogenic encephalopathy may increase morbidity or mortality, and in patients with AWS that is resistant to psychoactive drugs.
Dexamethasone has been shown to be efficacious in the treatment of patients with delirium tremens, (1), and was especially
Pol S, Nalpas B, Berthelot P. Dexamethasone for Alcohol Withdrawal. Ann Intern Med. ;114:705–706. doi: 10.7326/0003-4819-114-8-705
Download citation file:
Published: Ann Intern Med. 1991;114(8):705-706.
Tobacco, Alcohol, and Other Substance Abuse.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use