FRANKLIN B. PECK, M.D., F.A.C.P.
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The number of possible modifications of insulin is almost unlimited. Within the last few years several new preparations have been described1, 2, 3 and each has seemed to possess certain more or less specific advantages.4, 5, 6 Nevertheless, in common with protamine zinc insulin these modifications must of necessity be prepared with definite proportions of ingredients so each has its own individual time-activity, with onset and duration of physiologic action constant for each fixed combination. Each of these modifications provides a curve of time-activity which fits the needs of a limited group of diabetic patients almost perfectly.6 But judging from
PECK FB. APPROXIMATE INSULIN CONTENT OF EXTEMPORANEOUS MIXTURES OF INSULIN AND PROTAMINE ZINC INSULIN1. Ann Intern Med. ;18:177–181. doi: 10.7326/0003-4819-18-2-177
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Published: Ann Intern Med. 1943;18(2):177-181.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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