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In a previous communication these writers had shown that purified extracts of the duodenal and jejunal mucosa when injected intravenously cause the gall-bladder to contract and to exert pressure on its contents and at the same time excite the pancreas to secrete. Since that report Kloster, Lueth and Ivy have made preparations the use of which indicates that "secretin" does not cause the gall-bladder to contract, but that it is some substance closely associated with secretin, because it is possible to prepare a solution of secretin which is free of the gall-bladder excitant. In more than ten experiments the writers
Observations on the Cause of Gall-bladder Contraction and Evacuation.. Ann Intern Med. 1928;1:626. doi: https://doi.org/10.7326/0003-4819-1-8-626_1
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Published: Ann Intern Med. 1928;1(8):626.
Biliary Disorders, Gastroenterology/Hepatology.
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