ELLIOTT P. JOSLIN, M.D.
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In the same serious spirit with which Brace1 approached the problem of the effect of insulin upon the carbohydrate tolerance of diabetics, I have searched my own records and have reached a contrary and more optimistic conclusion and, I trust, explained his less favorable results. If he should reduce the total caloric intake of his patients to levels such as are accepted as normal for healthy individuals, thus involving a reduction of fat in the diet he prescribed, I believe he would be able to increase the carbohydrate in the course of a year with negligible or little increase in
JOSLIN EP. Insulin and Carbohydrate Tolerance1. Ann Intern Med. 1929;2:1001–1012. doi: 10.7326/0003-4819-2-10-1001
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Published: Ann Intern Med. 1929;2(10):1001-1012.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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