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In a paper published in 1914 Buerger expressed his conviction that the acutely inflamed veins and nodosities of thrombo-angiitis obliterans could furnish the material in which an infectious agent-virus or micro-organism might reside and be brought to light; second, that these foci might be utilized for the reproduction of the acute lesions of the malady. He has carried out investigations extending over ten or more years in the attempt to find a micro-organism. Failing in this effort he turned his attention to the reproduction of the acute lesions of the disease. He employed simple ligation of the veins of the
Thrombo-Angiitis Obliterans. Experimental Reproduction of Lesions.. Ann Intern Med. 1929;3:287. doi: 10.7326/0003-4819-3-3-287_1
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Published: Ann Intern Med. 1929;3(3):287.
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