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While at the present time no adequate clinical differentiation between the various forms of chronic splenomegaly is possible, a classification of an imperfect kind, based on differences in pathological anatomy and histology, has been attempted. The question of how far bacteriological methods may influence classification, and whether, for instance, aspergillum-like organisms are of etiological importance, is left open for further investigation. McNee's classification of chronic splenomegaly of unknown or uncertain origin is, as follows:
1. Splenomegaly with peri-ellipsoidal hæmorrhages and nodular siderosis (?? splenic mycosis).
2. Chronic hemolytic (acholuric) jaundice.
3. Thrombo-phlebitic splenomegaly.
4. Chronic splenic hypertrophy, with or without
A Tentative Classification of the Forms of Chronic Splenomegaly of Unknown or Uncertain Origin.. Ann Intern Med. 1929;3:506. doi: 10.7326/0003-4819-3-5-506_1
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Published: Ann Intern Med. 1929;3(5):506.
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