L. H. NEWBURGH; MARGARET WOODWELL JOHNSTON
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The physician who prescribes a low calorie diet to reduce the weight of his obese patients frequently deals with subjects who fail to lose weight during the period of observation. And the writers have satisfied their desire for an explanation of this seemingly paradoxical phenomenon by attributing it to abnormality of the endocrine glands—in particular the hypophysis, the thyroid, and the gonads. The logical conclusion to be reached from such a position is that these patients are the unfortunate victims of constitutional disease that unrelentingly causes a progressive deposition of adipose tissue, independent of activity or dietary habit. It is
NEWBURGH LH, JOHNSTON MW. Endogenous Obesity—A Misconception1. Ann Intern Med. 1930;3:815–825. doi: 10.7326/0003-4819-3-8-815
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Published: Ann Intern Med. 1930;3(8):815-825.
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