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These workers succeeded in producing a superinfection in a case of paresis, by inoculating spirochete material from the testicular syphilitic lesion of a rabbit. This superinfection ran a course without symptoms—a chancre immunity; the superinfection was proved to exist by the successful inoculation of extirpated inguinal nodes into a mouse and thence into a rabbit. Such a symptomless superinfection in syphilitic men had already been demonstrated by Kolle and his colleagues in experimentally infected rabbits. Such experiments would seem to indicate that the immunity of the syphilitic individual, even as in animals, is only an apparent immunity, a chancre immunity,
Syphilis Immunity and Syphilitic Superinfection without Symptoms in the Human Individual.. Ann Intern Med. 1930;3:1061. doi: https://doi.org/10.7326/0003-4819-3-10-1061_1
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Published: Ann Intern Med. 1930;3(10):1061.
Infectious Disease, Sexually Transmitted Infections.
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