ALLEN C. NICKEL
A causative organism of peptic ulcer was searched for in surgically resected tissue as well as in the various foci of infection and in the experimental lesions. In making cultures from the tissue, the tissue was crushed, finely macerated in a sterile mortar, with sterile sand, and then inoculated into various culture mediums. Control cultures also were made from pieces of apparently normal stomach and normal duodenal mucosa. Cultures from tonsils, extracted teeth and infected prostate glands were made. These cultural methods have been described in detail in previous publications. The cultures were then injected intravenously into rabbits in an
NICKEL AC. Duodenitis, Duodenal Ulcer and Gastric Ulcer:: Experimental Lesions Produced with Streptococci Obtained from Surgically Resected Ulcer-bearing Tissue and from Other Foci of Infection1. Ann Intern Med. ;3:1084–1096. doi: 10.7326/0003-4819-3-11-1084
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Published: Ann Intern Med. 1930;3(11):1084-1096.
Gastroenterology/Hepatology, Infectious Disease, Peptic Disease, Peptic Ulcer, Streptococcal Infections.
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