E. L. WALSH, M.S.; A. C. IVY, Ph.D., M.D.
The most accepted general cause of the origin of gall stones is bile stasis. Beyond this, views vary widely. Naunyn1 believes that a second cause is an ascending infection which causes "the stone-forming catarrh of the vesical mucosa," the cholesterin and calcium of the stone coming from the inflamed mucosa. Although he admits that some cholesterin may come from the bile, he attaches no great significance to diet nor to changes in cholesterin metabolism. Aschoff and Bacmeister2 classify gall stones etiologically into two general divisions, (a) the non-inflammatory or metabolic, and (b) the inflammatory, believing that the origin of the
WALSH EL, IVY AC. Observations on the Etiology of Gall Stones1. Ann Intern Med. 1930;4:134–144. doi: 10.7326/0003-4819-4-2-134
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Published: Ann Intern Med. 1930;4(2):134-144.
Biliary Disorders, Gastroenterology/Hepatology.
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