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Two years ago the authors noted a local disappearance of fat in insulin-treated children. They came to the conclusion that it was very probable that the local lipodystrophy was due to the trikresol added to the insulin for purposes of preservation of the latter. Depisch (Wien. Med. Wschr. 80, 168, 1930) made observations also on this local lipodystrophy and came to the following conclusions: In about 10 per cent of insulin-treated patients there develops, after 2 months to 2 years, a disappearance of adipose tissue in those skin areas in which the injections have been given. This lipodystrophy is more
Die Insulinlipodystrophie bei Kindern.. Ann Intern Med. ;4:407. doi: 10.7326/0003-4819-4-4-407_1
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Published: Ann Intern Med. 1930;4(4):407.
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