J. SHIRLEY SWEENEY, M.D., Sc.D., F.A.C.P.
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Agranulocytosis was first reported by Schultz in 1922. In the last seven years, many observers have added cases. The number has amounted now to nearly one hundred cases1. When one reviews the literature on this disease, he is impressed with its protean manifestations. Blumer2 has recently drawn attention to the fact that all cases do not conform to Schultz' original description. One finds cases without anginal lesions, with anemia, with only moderate reduction of white cells, etc. The natural inference is, therefore, that agranulocytosis as an entity has not been completely described.
Much has been written in an effort to
SWEENEY JS. "Polymorphonuclear Leucopenia" A Proposed Classification. Ann Intern Med. 1930;4:494–497. doi: https://doi.org/10.7326/0003-4819-4-5-494
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Published: Ann Intern Med. 1930;4(5):494-497.
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