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For a number of years we have noted that the livers of patients dying with exophthalmic goiter in the University Hospital presented significant pathologic changes. Many showed some degree of simple or pigment atrophy, but the most common and striking hepatic change was the very frequent occurrence of a marked diffuse fatty degenerative infiltration, bearing all the earmarks of a severe toxic process. In a number of cases this lesion has been so marked as to call forth comparisons with the classical phosphorus liver. To make the resemblance to the latter condition more close, the hearts and kidneys of the
HEPATIC LESIONS ASSOCIATED WITH EXOPHTHALMIC GOITER. Ann Intern Med. 1930;4:501–505. doi: https://doi.org/10.7326/0003-4819-4-5-501
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Published: Ann Intern Med. 1930;4(5):501-505.
Endocrine and Metabolism, Thyroid Disorders.
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