HENRY J. VANDEN BERG, M.D., F.A.C.S.
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The heart seems to be the first organ to show definitely the effects of thyroid toxicity. With this statement everyone seems to agree. This toxicity is manifested early in the heart action in that the rate is accelerated and the force of the beat is increased. Acceleration of the heart rate is one of the most common physical signs one meets in clinical medicine, whereas cardiac overaction occurs in comparatively few conditions. It may be presumed that all organs and tissues are affected by thyroid toxicity, but none can be so advantageously measured and studied as the heart, both because
VANDEN BERG HJ. Cardiac Overaction: The Most Constant and Most Dependable Sign in Thyroid Toxicity*. Ann Intern Med. 1931;4:1406–1410. doi: https://doi.org/10.7326/0003-4819-4-11-1406
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Published: Ann Intern Med. 1931;4(11):1406-1410.
Cardiology, Emergency Medicine, Endocrine and Metabolism, Thyroid Disorders.
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