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The blood sugar values recorded generally in the literature represent the sum of the sugar and non-sugar reducing substances present. Somogyi has perfected a simple method of precipitation with zinc salts whereby, together with the blood proteins, the reducing non-sugars also are precipitated and thus filtrates are obtained that contain no appreciable amount of reducing substances other than sugar. Using such zinc filtrates, true sugar values are obtained in a single determination by any of the titrimetric or colorimetric methods in general use. The author determined the fasting true blood sugar in 100 normal adults, 50 men and 50 women.
The Blood Sugar of Normal Fasting Persons.. Ann Intern Med. 1931;5:390. doi: 10.7326/0003-4819-5-3-390_1
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Published: Ann Intern Med. 1931;5(3):390.
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