ALEX M. BURGESS, M.D., F.A.C.P.
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Since the introduction of the use of amyl nitrite by Sir Lauder Brunton in 1867 nothing has been found to excel the nitrites for the relief of the pain in angina pectoris. Although the pharmacology of the members of this group has been exhaustively studied the question as to the mode of their action in anginal pain has never been definitely settled. This is due partly to the fact that the cause of the pain has not been thoroughly understood. Furthermore, because of their known action on the walls of the peripheral arterioles resulting in a lowering of blood pressure,
BURGESS AM. The Reaction to Nitrites in the Anginal Syndrome and Arterial Hypertension*. Ann Intern Med. 1931;5:441–462. doi: https://doi.org/10.7326/0003-4819-5-4-441
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Published: Ann Intern Med. 1931;5(4):441-462.
Cardiology, Coronary Heart Disease, Coronary Risk Factors, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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