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Three groups of experimental animals (guinea pigs) were established. To those in the first group viosterol was given daily for 7 to 10 days. After this preliminary treatment, the animals were injected daily with parathormone in increasing amounts, and the viosterol was also continued. This combined medication extended over a period of 23 days. In a second group viosterol and parathormone were started simultaneously and administration extended over a period of 29 days. The third group contained 6 controls which were injected with parathormone as in the second group, but these animals did not receive viosterol. The animals in all
Viosterol Treatment in Experimental Hyperparathyroidism.. Ann Intern Med. ;5:943. doi: 10.7326/0003-4819-5-7-943_2
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Published: Ann Intern Med. 1932;5(7):943.
Endocrine and Metabolism, Parathyroid Disorders.
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