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From a study of the geographical distribution of 64 cases of myxedema in the series studied, and in comparison with the usual clinical experience in other regions, it is concluded that this disease is more common in the Great Lakes goiter district than in nongoitrous regions. In the series studied, 75 per cent of the patients were female; and 34 of the 64 were in the age-group 41-60. In 40 per cent the basal metabolic rate was between 15 per cent and 25 per cent below normal. The most common presenting symptom of the patients in this group was weakness.
A Clinical Study of Myxedema in Michigan.. Ann Intern Med. 1932;5:1042. doi: https://doi.org/10.7326/0003-4819-5-8-1042_3
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Published: Ann Intern Med. 1932;5(8):1042.
Endocrine and Metabolism, Thyroid Disorders.
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