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The geographical distribution of exophthalmic goiter, when correlated with possible specific factors, may yield information of value in respect to the etiology of this disease. This is a field of investigation which is far from being exhausted. A simultaneous study of other diseases of endocrine dysfunction and of metabolic exhaustion, such as diabetes and pernicious anemia, should be of value as a control. Using mortality statistics as a basis, and calculating the deaths from each disease as a percentage of the total number of deaths in given areas, distribution maps have been prepared for North America, and likewise climate maps
Climate as a Potential Factor in the Etiology of Exophthalmic Goiter and the Other Metabolic Diseases.. Ann Intern Med. ;5:1198. doi: 10.7326/0003-4819-5-9-1198_1
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Published: Ann Intern Med. 1932;5(9):1198.
Endocrine and Metabolism, Thyroid Disorders.
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