B. J. CLAWSON, M.D.; M. WETHERBY, M.D.
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The factors considered as a basis for intravenous streptococcic vaccination reported in this paper are (1) etiology and (2) a method of vaccination which will not produce hypersensitiveness (allergy) but will desensitize patients already hypersensitive and will produce a high degree of protective immunity.
The belief that most cases of chronic arthritis are infectious in origin is quite generally accepted. The exact infectious agent and the manner and the form in which the agent finds its way into the joints are not so generally agreed upon. Some people believe that there is a direct infection of the joint by
CLAWSON BJ, WETHERBY M. An Experimental Basis for Intravenous Vaccine Therapy in Chronic Arthritis With a Summary of Results Obtained in Patients*†. Ann Intern Med. 1932;5:1447–1461. doi: https://doi.org/10.7326/0003-4819-5-12-1447
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Published: Ann Intern Med. 1932;5(12):1447-1461.
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