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Feeding winter cabbage in the early part of 1931 to 17 rabbits for periods up to 114 days produced hyperplasia of the thyroid, but in only two instances were enlargements to more than twice the normal weight obtained. The microscopic changes were more conspicuous than the gross enlargement. The data obtained support the view of Webster, Marine and Cipra that there is an annual variation in the goiterogenic agent in cabbage, as well as seasonal differences and differences in the susceptibility of individual rabbits.
The Effect of Cabbage Feeding on the Morphology of the Thyroid of Rabbits.. Ann Intern Med. 1932;6:451. doi: https://doi.org/10.7326/0003-4819-6-3-451_1
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Published: Ann Intern Med. 1932;6(3):451.
Endocrine and Metabolism, Thyroid Disorders.
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