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The results of previous researches have seemed to indicate that the normal stomach secretes a substance (probably the same as that which Castle has shown to be present) which, while without effect on the reticulocytes when administered orally, might cause a response if it could be administered parenterally. This assumption has been tested by the intramuscular injection of neutralized sterile gastric juice and also of a concentrate of normal human gastric juice obtained by evaporation in vacuo. The results prove the presence in normal gastric juice of a powerful bone marrow stimulant, producing not only a marked and very rapid
The Hematopoietic Response in Pernicious Anemia Following the Intramuscular Injection of Gastric Juice.. Ann Intern Med. 1933;6:961. doi: 10.7326/0003-4819-6-7-961_1
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Published: Ann Intern Med. 1933;6(7):961.
Hematology/Oncology, Red Cell Disorders.
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