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Clinical evidence of disturbance of the liver in hyperthyroidism is afforded by occasional cases of icterus in association with thyrotoxicosis for which no other cause can be discovered. Hepatic changes, even a fully developed interlobular cirrhosis, have been discovered in some cases of hyperthyroidism. Thyroid substance, or thyroxin, causes the glycogen to disappear from the liver. The author investigated the liver function in a series of twenty consecutive cases of hyperthyroidism, making use, among other methods, of an original cinchophen oxidation test. A disturbance in the oxidation of cinchophen was demonstrated in 16 of the 20 cases, the results indicating
Liver Function in Hyperthyroidism.. Ann Intern Med. 1933;6:961–962. doi: 10.7326/0003-4819-6-7-961_3
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Published: Ann Intern Med. 1933;6(7):961-962.
Endocrine and Metabolism, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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