EARLE A. HARVEY, M.D.; WILLIAM P. MURPHY, M.D.
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Changes in the stomach or in its secretions have been noted as a common finding in pernicious anemia for many years. As early as 1860 Austin Flint1 spoke of an absence of gastric secretion and mentioned degenerative changes in the gastric mucosa. In 1877 Fenwick2 noted atrophy of the gastric mucous membrane. Achlorhydria was spoken of by Cahn and von Mering3 as early as 1886 and again by von Noorden4 in 1891. Since these early reports, the absence of free hydrochloric acid from the gastric juice and a low total or combined acidity has usually been considered to be a
HARVEY EA, MURPHY WP. Pernicious Anemia without Achlorhydria*†: Case Report. Ann Intern Med. 1933;6:1393–1406. doi: https://doi.org/10.7326/0003-4819-6-11-1393
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Published: Ann Intern Med. 1933;6(11):1393-1406.
Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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