BYRON D. BOWEN, M.D., F.A.C.P.; GILBERT BECK, M.D.
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The reaction of the body to hypoglycemia, caused by unbuffered insulinism of endogenous or exogenous source, constitutes a recent chapter in medicine. This communication deals chiefly with this response as it occurs in the treatment of diabetes with insulin.
We have divided the insulin reaction into two phases, largely for the sake of convenience of description. The first is characterized by nervousness, perspiration, pallor, tremor, palpitation, weakness, hunger, and a peculiar sense of "goneness". The second indicates a disturbance of the central nervous system and presents a wide variety of symptoms. Of these the most frequently observed are diplopia, paresthesias
BOWEN BD, BECK G. Insulin Hypoglycemia*†: Two Cases with Convulsions; One Necropsy Report. Ann Intern Med. 1933;6:1412–1425. doi: https://doi.org/10.7326/0003-4819-6-11-1412
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Published: Ann Intern Med. 1933;6(11):1412-1425.
Neurology, Seizure Disorders.
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