GEORGE A. HARROP, M.D., F.A.C.P.
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Although the first accurate description of the adrenal glands is usually accredited to Eustachius, in 1563, very little further progress was made in the study of their structure or physiological significance for nearly three centuries and practically all of the further additions to our knowledge have been made within the past eighty years. Modern interest in the adrenals dates from Addison, who published in 1855 the clinical observations on the disease which bears his name.
In all mammals, including man, the adrenal glands are paired organs, each composed of two distinct parts. The outer layer, or cortex, forms roughly two-thirds
HARROP GA. Addison's Disease and Its Relation to Experimental Adrenal Insufficiency*†. Ann Intern Med. 1933;6:1579–1590. doi: https://doi.org/10.7326/0003-4819-6-12-1579
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Published: Ann Intern Med. 1933;6(12):1579-1590.
Adrenal Disorders, Endocrine and Metabolism.
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