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Original Research |1 July 1933

ULTRAHIGH FREQUENCY PYRETOTHERAPY OF NEUROSYPHILIS1: A Preliminary Report

WALTER M. SIMPSON, M.S., M.D., F.A.C.P.; FRED K. KISLIG, M.D., F.A.C.S.; EDWIN C. SITTLER, B.S. (ENG.)

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
Paragraph71353*From the Diagnostic Laboratories, Venereal Clinic and Radiotherm Department of the Miami Valley Hospital and the Research Laboratory of the Frigidaire Corporation, Dayton, Ohio.
Paragraph71355This investigation was made possible by a grant from the Charles F. Kettering Foundation.
Paragraph71357Presented at the Seventeenth Annual Clinical Session of the American College of Physicians, Montreal, February 8, 1933.
Paragraph71359†Doctor Kislig died on February 7, 1933.
Paragraph71361‡With the coöperation of Charles F. Kettering, Sc.D., William Nesser, M.E., Thomas P. Sharkey, M.D., Worley Kendell, M.D., Arthur M. Culler, M.D., Eunice Fraizer, M.S., Carl McD. Ritter, B.S., Florence Storck, R.N., and Kathryn Rife, R.N.
Paragraph71363§This investigation had its inception in ideas expressed in a book by Paul de Kruif, Ph.D., entitled "Men Against Death," Harcourt, Brace and Co., N. Y., Chapt. 9, pp. 267-279.
  • Paragraph71353*From the Diagnostic Laboratories, Venereal Clinic and Radiotherm Department of the Miami Valley Hospital and the Research Laboratory of the Frigidaire Corporation, Dayton, Ohio.
  • Paragraph71355This investigation was made possible by a grant from the Charles F. Kettering Foundation.
  • Paragraph71357Presented at the Seventeenth Annual Clinical Session of the American College of Physicians, Montreal, February 8, 1933.
  • Paragraph71359†Doctor Kislig died on February 7, 1933.
  • Paragraph71361‡With the coöperation of Charles F. Kettering, Sc.D., William Nesser, M.E., Thomas P. Sharkey, M.D., Worley Kendell, M.D., Arthur M. Culler, M.D., Eunice Fraizer, M.S., Carl McD. Ritter, B.S., Florence Storck, R.N., and Kathryn Rife, R.N.
  • Paragraph71363§This investigation had its inception in ideas expressed in a book by Paul de Kruif, Ph.D., entitled "Men Against Death," Harcourt, Brace and Co., N. Y., Chapt. 9, pp. 267-279.
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Abstract

It is now generally agreed that fever is essentially a protective and defensive mechanism. It is known that the fever which accompanies infection exerts an adverse influence upon the growth of bacteria, diminishes the potency of toxins, favors phagocytosis, and stimulates the development of immune bodies.1 The gradual abandonment of antipyretic drugs has naturally followed the recognition of these facts. More effective physical agents are now utilized to combat extreme hyperpyrexia.

The monumental researches of Wagner-Jauregg introduced artificially-induced fever as an important addition to the therapeutic armamentarium against many chronic afebrile diseases. The remarkable results which have been achieved with

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SIMPSON WM, KISLIG FK, SITTLER EC. ULTRAHIGH FREQUENCY PYRETOTHERAPY OF NEUROSYPHILIS1: A Preliminary Report. Ann Intern Med. ;7:64–75. doi: 10.7326/0003-4819-7-1-64

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Published: Ann Intern Med. 1933;7(1):64-75.

DOI: 10.7326/0003-4819-7-1-64

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