GERSON R. BISKIND, M.D.; NORMAN N. EPSTEIN, M.D.; WM. J. KERR, M.D., F.A.C.P.
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Patients undergoing routine antisyphilitic therapy occasionally develop hepatic disturbances. The liver of the individual with syphilis may be damaged by the disease or by untoward effects of antisyphilitic remedies, or by a combination of both. Latent disease of the liver may also be found in certain patients undergoing specific treatment, in whom the usual methods of clinical examination fail to reveal these pathologic processes. The clinical recognition of the acute phases of hepatic disease offers little difficulty. After the subsidence of the acute process, however, the determination of the exact status of the liver requires careful study.
BISKIND GR, EPSTEIN NN, KERR WJ. HEPATIC COMPLICATIONS IN THE TREATMENT OF SYPHILIS: THE ROSE BENGAL TEST AS A MEANS OF DETECTING DISTURBANCES OF LIVER FUNCTION AND ITS USE AS A GUIDE IN THE THERAPY OF SYPHILIS*. Ann Intern Med. 1934;7:966–980. doi: https://doi.org/10.7326/0003-4819-7-8-966
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Published: Ann Intern Med. 1934;7(8):966-980.
Infectious Disease, Sexually Transmitted Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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