JOHN A. KOLMER, M.D., F.A.C.P.
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Definition. While the condition septicemia is well understood clinically yet it is hard to define in a clear and concise manner; hence many definitions have been offered. It is characterized by pronounced signs and symptoms of infection due largely to the presence of pathogenic organisms and their products in the blood and is usually associated with infection of the fixed tissues. In my opinion it is best defined as an infection of the blood because this phase greatly predominates in the clinical manifestations.
Emphasis is placed upon infection of the blood with all it implies as differentiated from invasion of
KOLMER JA. SEPTICEMIA*. Ann Intern Med. 1934;8:612–631. doi: https://doi.org/10.7326/0003-4819-8-5-612
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Published: Ann Intern Med. 1934;8(5):612-631.
Multi-Organ Failure and Sepsis, Pulmonary/Critical Care.
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