JOHN A. TOOMEY, M.D., F.A.C.P.
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Faber1 believed that a good theory for the explanation of the virus spread in poliomyelitis in man would be to assume that, after the virus entered the system along the olfactory terminal fibers, it spread by way of the olfactory tracts, through the hypothalamus, to the medulla, thalamus and midbrain, and then down the spinothalamic tract to the posterior column, finally reaching the anterior horn cell area in the cord. However, the possibility of extension by other pathways was not denied. His hypothesis was based upon clinical findings and upon evidence that was obtained from experiments on monkeys
TOOMEY JA. AN EXPLANATION OF THE MECHANISM OF INFANTILE PARALYSIS PRODUCTION IN THE HUMAN BEING*. Ann Intern Med. 1935;8:854–864. doi: https://doi.org/10.7326/0003-4819-8-7-854
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Published: Ann Intern Med. 1935;8(7):854-864.
DOI: 10.7326/0003-4819-8-7-854
CNS Infections, Infectious Disease, Neurology.
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