NORBERT ENZER, M.D., F.A.C.P.; BENJAMIN LIEBERMAN, M.D.
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The renewed interest in diseases of bone apparent in current medical literature had its impetus in 1926 when Mandl, in a crucial clinical experiment, established the etiologic relationship between tumor of the parathyroids and von Recklinghausen's disease of bone (osteitis fibrosa cystica). This removed the disease from the category of a morphologic to that of an etiologic entity, as demonstrated by the numerous reports of cases which followed. On the basis of both clinical and experimental study, Jaffe,1 in his recent exhaustive review of the disease, indicates that the pathogenesis involves decalcification or demineralization of the skeletal system through the
ENZER N, LIEBERMAN B. MULTIPLE MYELOMA1. Ann Intern Med. 1935;8:1062–1070. doi: 10.7326/0003-4819-8-9-1062
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Published: Ann Intern Med. 1935;8(9):1062-1070.
Hematology/Oncology, Multiple Myeloma.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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