LOUIS A. MITCHELL, M.D.
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In 1913 Reschad and Schilling-Torgau1 reported the first case of monocytic leukemia to appear in the literature. Since then the disease has gradually gained recognition, and variations from its usual form, such as are found in association with other types of leukemia, have been observed. However, extensive tumor formation with primary multiple monoblastomata of the connective tissues ending in a terminal leukemic phase in which large numbers of primitive monoblasts flooded the peripheral circulation, such as is herewith described, has not previously been reported.
The acceptance of monocytic leukemia as a distinct disease has come through a recognition of the
MITCHELL LA. MALIGNANT MONOBLASTOMA: A VARIANT OF MONOCYTIC LEUKEMIA*. Ann Intern Med. 1935;8:1387–1403. doi: https://doi.org/10.7326/0003-4819-8-11-1387
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Published: Ann Intern Med. 1935;8(11):1387-1403.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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