GRACE M. ROTH, B.S.; CHARLES H. WATKINS, M.D., F.A.C.P.
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Although Hodgkin's1 disease was described by him as early as 1832, the blood picture in this disease was not seriously considered until 1910. At that time Fabian,2 after a critical survey of the literature, reported that the blood picture was not sufficiently constant to be of any diagnostic value. He did state, however, that the most frequent hematologic finding in Hodgkin's disease was a moderate increase in the number of polymorphonuclear neutrophiles and a relative decrease in the number of lymphocytes.
In 1911, following this survey, Bunting3 reported the analysis of a small series of blood counts in cases of
ROTH GM, WATKINS CH. THE LEUKOCYTE PICTURE IN HODGKIN'S DISEASE1. Ann Intern Med. ;9:1365–1372. doi: 10.7326/0003-4819-9-10-1365
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Published: Ann Intern Med. 1936;9(10):1365-1372.
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