WYATT C. SIMPSON, M.D.; J. ARNOLD BARGEN, M.D., F.A.C.P.
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Knowledge of the condition that is known as "chronic ulcerative colitis" seems to date at least to the "bloody flux" of Sydenham, in 1669.
Its bacterial etiology has been recognized only recently. Etiologic significance has generally been ascribed to the diplostreptococcus originally described by one of us.
The similarity of this disease, because of its destructive character, to tuberculosis has frequently been emphasized. This fact has made it difficult to evaluate any single therapeutic agent employed in its treatment. Even though many clinicians seem to recognize its similarity to tuberculosis they frequently have not comprehended the importance of a therapeutic
SIMPSON WC, BARGEN JA. CHRONIC ULCERATIVE COLITIS: FACTORS INFLUENCING ITS RESPONSE TO SPECIFIC TREATMENT*. Ann Intern Med. 1937;10:1551–1555. doi: https://doi.org/10.7326/0003-4819-10-10-1551
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Published: Ann Intern Med. 1937;10(10):1551-1555.
Gastroenterology/Hepatology, Inflammatory Bowel Disease.
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