ISADORE OLEF, M.D.
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Chlorosis is defined by Patek and Heath1 as "a hypochromic anemia in adolescent girls and young women, usually associated with gastrointestinal and menstrual disorders." According to many observers, Naegeli2 and Witts3 among others, this condition, previously common, has become a disease largely of historical interest. Many of the younger clinicians who have not seen typical cases of classical adolescent chlorosis are inclined to doubt altogether the existence of this type of anemia. There is no doubt that chlorosis was quite frequent a quarter of a century ago. Its high incidence then, however, was more apparent than real. This is obvious
OLEF I. CHLOROSIS1. Ann Intern Med. ;10:1654–1663. doi: 10.7326/0003-4819-10-11-1654
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Published: Ann Intern Med. 1937;10(11):1654-1663.
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