ROBERT H. WILLIAMS, M.D.
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It has been known for many years that the gonococcus is quite susceptible to heat.1, 2 It remained for Carpenter, Boak, Mucci and Warren3 to determine by careful thermal death time gradient studies that 99 per cent of the cultures of several strains of gonococci are killed in vitro by 4 to 5 hours exposure to a temperature of 105.8° F. With the Kettering hypertherm even higher temperatures over longer periods of time may be administered to patients with comparative safety. The excellent clinical results obtained with this form of treatment in various gonococcal infections strongly suggest that the thermal
WILLIAMS RH. GONOCOCCAL ENDOCARDITIS TREATED WITH ARTIFICIAL FEVER (KETTERING HYPERTHERM)*. Ann Intern Med. 1937;10:1766–1774. doi: https://doi.org/10.7326/0003-4819-10-12-1766
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Published: Ann Intern Med. 1937;10(12):1766-1774.
Cardiology, Endocarditis, Infectious Disease, Sexually Transmitted Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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