JANVIER W. LINDSAY, M.D., F.A.C.P.; E. CLARENCE RICE, M.D., F.A.C.P.; MAURICE A. SELINGER, M.D.; K. HAMMOND MISH, M.D.
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Protamine insulin was first used in the United States during 1935 by Root,1 Joslin2 and their associates and since then its use has been extended to diabetic patients in other parts of the country under the direction of physicians with considerable experience in the treatment of diabetes mellitus. The number under treatment at present in the United States is probably about 3,000 persons.
By means of its use it has been possible to convert the severe diabetes of a number of patients not easily controlled by the simpler or regular insulin to a relatively mild form due to the prolonged
LINDSAY JW, RICE EC, SELINGER MA, et al. PROTAMINE INSULIN AS A CONTRIBUTING FACTOR IN THE DEATH OF A DIABETIC PATIENT WITH CEREBRAL ARTERIOSCLEROSIS*. Ann Intern Med. 1937;10:1892–1900. doi: https://doi.org/10.7326/0003-4819-10-12-1892
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Published: Ann Intern Med. 1937;10(12):1892-1900.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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