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Serum therapy is an outgrowth of the discovery that microörganisms, the bacteria, are incitants of infectious disease. As such, it is difficult to differentiate the results of the branch from those of the parent stem. For example, in diphtheria, early diagnosis with prompt isolation has alone had a far-reaching effect not only upon the morbidity but also, indirectly, upon the severity of the disease; and it is difficult to distinguish the effect of the discovery of the diphtheria bacillus and of improved public health methods from that of the specific treatment with antitoxin, on the morbidity and mortality of the
WADSWORTH A. AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATT: SOME OF THE PRACTICAL PROBLEMS IN THE SERUM THERAPY OF BACTERIAL INFECTIONS1. Ann Intern Med. ;11:791–800. doi: 10.7326/0003-4819-11-5-791
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Published: Ann Intern Med. 1937;11(5):791-800.
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