HAROLD W. JONES, M.D., F.A.C.P.; LEANDRO M. TOCANTINS, M.D.; RICHARD MANGES SMITH, M.D.
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Our experience with splenic irradiation in purpura hemorrhagica is not in agreement with that of Mettier,1 who states, "Repeated roentgen irradiation over the spleen in suitable doses is an excellent means of increasing the number of circulating blood platelets in patients with idiopathic thrombo-cytopenic purpura hemorrhagica."
The term control of coagulation was used loosely, and still is, by some to include control of bleeding of any type without attempting to isolate that occurring in purpura hemorrhagica. Therefore, many data reported in the literature can not be considered as significant. Costa Storicco2 states that as early as 1912 Triboulet,
JONES HW, TOCANTINS LM, SMITH RM. AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DR. JOSEPH HERSEY PRATT: SPLENIC IRRADIATION IN THE TREATMENT OF PURPURA HEMORRHAGICA1. Ann Intern Med. ;11:1311–1331. doi: 10.7326/0003-4819-11-7-1311
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Published: Ann Intern Med. 1938;11(7):1311-1331.
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