HENDRIK M. ROZENDAAL, M.D.; RICHARD N. WASHBURN, M.D.
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Many authors believe that achlorhydria is a constant finding in cases of pernicious anemia. There are, however, a number of reported cases of pernicious anemia in which free hydrochloric acid was present in the gastric contents. Alsted was able to collect 32 such cases from the literature.
The cause of the achlorhydria in these cases is unknown. Faber was of the opinion that achlorhydria is always the result of atrophic gastritis which, according to him, is a constant finding in cases of pernicious anemia. Hurst, on the other hand, emphasized the constitutional factor in achlorhydria. The frequent familial occurrence of
ROZENDAAL HM, WASHBURN RN. GASTRIC SECRETION IN CASES OF PERNICIOUS ANEMIA*. Ann Intern Med. 1938;11:1834–1837. doi: https://doi.org/10.7326/0003-4819-11-10-1834
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Published: Ann Intern Med. 1938;11(10):1834-1837.
Hematology/Oncology, Red Cell Disorders.
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