JESSE L. BOLLMAN, M.D.
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Our fundamental knowledge of the functions of the liver is based on physiologic studies of that organ. We have learned from observation of animals after complete removal of the liver that this organ is essential for the maintenance of the sugar of the blood. Jaundice develops in hepatectomized animals, but the liver is necessary to convert bilirubin which reacts indirectly to the van den Bergh test to direct reacting bilirubin.
Many other metabolic processes have been shown to be entirely dependent on the liver.1 Such functions are but rarely found to be materially impaired in the presence of hepatic disease
BOLLMAN JL. SOME EXPERIMENTAL OBSERVATIONS PERTINENT TO THE TREATMENT OF HEPATIC DISEASE1. Ann Intern Med. 1938;12:1–5. doi: 10.7326/0003-4819-12-1-1
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Published: Ann Intern Med. 1938;12(1):1-5.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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