OTTO T. BROSIUS, M.D., D.T.M. & H., F.A.C.P.
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To be tremendously over-rated when first introduced is quite a characteristic event in the history of all new remedial agents—especially of specifics. Then after the pendulum has swung in the opposite direction through the condemnations of the ultra-conservatives a return towards a correct estimate of the remedial measure may be expected.
Practically ever since the historical occasion when a decoction from the bark of a Peruvian tree first effected a spectacular cure in the oft-cited case of Cinchona, the wife of the Spanish Viceroy to Perú, substitutes for this bark and its derivatives have been eagerly sought because of the
BROSIUS OT. QUININE AND ATEBRINE—A COMPARISON1. Ann Intern Med. ;12:353–364. doi: 10.7326/0003-4819-12-3-353
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Published: Ann Intern Med. 1938;12(3):353-364.
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