A. C. WOOFTER, B.S., M.D.; B. S. PARKS, M.D., M.Sc.
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The term "hemoglobinuria" is used to designate the excretion of blood pigment in the urine with total absence of red blood cells, or with only a relatively small number that cannot be considered sufficient to explain the altered, bloody or dark blood like, appearance of the specimen.
This phenomenon is observed: (1) when hemoglobin in sufficient quantity is injected into the blood stream; (2) after procedures resulting in solution of the red blood cells, such as transfusion of blood, or the injection intravenously of incompatible blood serum of another species, of distilled water, glycerine, oil or many other chemical substances;
WOOFTER AC, PARKS BS. PAROXYSMAL HEMOGLOBINURIA WITH REPORT OF A CASE*. Ann Intern Med. 1938;12:402–406. doi: https://doi.org/10.7326/0003-4819-12-3-402
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Published: Ann Intern Med. 1938;12(3):402-406.
Hematology/Oncology, Red Cell Disorders.
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