ERNEST W. GOODPASTURE
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Although physical and chemical methods, especially the former, are being employed extensively at the present time in efforts to elucidate the size, shape, composition and general properties of the ultimate virus particles, an exact determination of their nature as a class has not yet been arrived at; and it is still necessary to resort to the biological method of infecting susceptible hosts, whether cell-suspensions or organized animals and plants, in order to demonstrate and to study the activity of these agents.
Manifestation of a virus activity involves interactions between it and living susceptible cells, in the course of which virus
GOODPASTURE EW. VIRUS INFECTION OF THE CHICK EMBRYO*. Ann Intern Med. 1939;13:1–11. doi: https://doi.org/10.7326/0003-4819-13-1-1
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Published: Ann Intern Med. 1939;13(1):1-11.
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